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1 Are There Alternatives to the Use of Animals in Research?
https://www.nap.edu/read/10089/chapter/8
Most researchers generally hold that nonanimal experiments are adjuncts rather than alternatives to animal experiments. Studies that do not use animals can ...
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2 Alternatives to Animal Testing
https://www.niehs.nih.gov/health/topics/science/sya-iccvam/index.cfm
Alternatives to Animal Testing · Biomarkers · Chemical Mixtures · Epigenetics · Exposure Science · Gene and Environment Interaction · Microbiome · Toxicology.
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3 No alternative to animal tests for behaviour - Nature
https://www.nature.com/articles/419337b
It is not possible to replace such tests with non-animal methods using, for example, human cells or yeast.
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4 Alternatives to animal testing | Cruelty Free International
https://crueltyfreeinternational.org/about-animal-testing/alternatives-animal-testing
› about-animal-testing
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5 Alternatives to animal testing: A review - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1319016413001096
Various alternatives to the use of animals have been suggested, such as in vitro models, cell cultures, computer models, and new imaging/analyzing techniques ( ...
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6 Do “Alternatives” Exist? - Speaking of Research
https://speakingofresearch.com/extremism-undone/alternatives/
Again, although the aim is to refine the models and reduce the number of animal experiments, Stephens notes that in vitro testing cannot replace animal testing ...
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7 Alternatives to animals
https://www.asbmb.org/asbmb-today/science/071421/alternatives-to-animals
Although it may seem counterintuitive, sometimes an individual experiment must use more animals to avoid wasting animal lives. If an ...
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8 What Are the Alternatives to Animal Testing? - Live Science
https://www.livescience.com/65401-animal-testing-alternatives.html
› 65401-animal-testing-alt...
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9 Save the Animals: Stop Animal Testing | - Lone Star College
https://www.lonestar.edu/stopanimaltesting.htm
Although humans often benefit from successful animal research, the pain, the suffering, and the deaths of animals are not worth the possible human benefits.
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10 Alternatives to animal testing - Wikipedia
https://en.wikipedia.org/wiki/Alternatives_to_animal_testing
Other alternatives include the use of humans for skin irritancy tests and donated human blood for pyrogenicity studies. Another alternative is so-called ...
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11 Will we ever… eliminate animal experimentation? - BBC Future
https://www.bbc.com/future/article/20130609-will-we-ever-end-animal-testing
There are two reasons for this, says Thomas Hartung, Director of the Center for Alternatives to Animal Testing at Johns Hopkins University, in ...
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12 Finding alternatives to animal testing | University of California
https://www.universityofcalifornia.edu/news/finding-alternatives-animal-testing
Scientists have known for a long time that animals differ from humans in important developmental and physiological ways, and that animal test ...
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13 Alternatives to animal testing - Chemicals In Our Life - ECHA
https://chemicalsinourlife.echa.europa.eu/alternatives-to-animal-testing
They need to share information and test results on their chemical so that there is no need to repeat animal studies. They then need to agree on whether new ...
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14 Yes, Dad, There Are Alternatives
https://caat.jhsph.edu/publications/Articles/aavs.html
His response isn't altogether wrong, either. Not all animal research or testing can be replaced by non-animal methods at this time — and some may never be. I ...
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15 Animal Testing and Alternatives
https://www.pcrm.org/ethical-science/animal-testing-and-alternatives
› ethical-science › animal-testing...
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16 Alternatives to animal experimentation in basic research
https://www.altex.org/index.php/altex/article/view/2182
In contrast to animal testing required by law to guarantee minimum safety standards for the licensing of drugs and chemicals, there are no ...
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17 Chapter 24 Recent Developments in Alternatives to Animal ...
https://brill.com/display/book/edcoll/9789004391192/BP000031.xml
Interventions can include testing substances (such as cosmetic products, industrial chemicals, drugs, pesticides, food additives, and biocides); ...
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18 Alternatives to animal testing | Unilever
https://www.unilever.com/planet-and-society/responsible-business/alternatives-to-animal-testing/
All our PETA-approved brands and products go beyond the standard requirements of the EU Cosmetics Regulation to ensure there is no animal testing conducted ...
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19 Animal testing and experiments FAQ
https://www.humanesociety.org/resources/animals-used-experiments-faq
There is no limit to the extent of pain and suffering that can be inflicted on animals during experiments. In some instances, animals are not given anything to ...
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20 Alternatives to Animal Use in Testing - Princeton University
https://www.princeton.edu/~ota/disk2/1986/8601/860110.PDF
Test- ing is an integral part of many regulatory schemes and product liability law, and validation ultimately rests on acceptance by the scientific, regulatory,.
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21 How viable are alternatives to animal testing in determining ...
https://www.tandfonline.com/doi/full/10.1080/17425255.2019.1694662
A revolution in thinking and practice is needed, involving an escape from relying on animal tests, and resulting in a strong and convincing ...
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22 The 3Rs: What are Medical Scientists Doing about Animal ...
https://kids.frontiersin.org/articles/10.3389/frym.2018.00044
The ultimate replacement for animal experiments would be to use humans or human blood or tissue samples, as the results of human experiments ...
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23 Animal Experiments | Humane Alternatives - RSPCA
https://www.rspca.org.uk/adviceandwelfare/laboratory/replacinganimals
Altweb - Alternatives to Animal Testing Website · Animal Free Research UK - Replacing Animals in Medical Research · FRAME - Fund for the Replacement of Animals in ...
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24 Alternatives to animal research - Norecopa
https://norecopa.no/alternatives
Alternatives to animal experiments may be summarised as "The Three Rs", a concept described by Russell and Burch.
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25 Should Computer Simulations Replace Animal Testing for ...
https://www.scientificamerican.com/article/should-computer-simulations-replace-animal-testing-for-heart-drugs/
Animal testing has, to date, been the most accurate and reliable strategy ... alternative to animal experiments—and they will soon play an ...
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26 Alternatives to Animal Experimentation: Its Institutional ...
https://www.intechopen.com/chapters/60728
Although it is desirable to replace scientific procedures with live animals by other methods that do not use them, the use of animals in scientific ...
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27 Scientific Alternatives to Animal Testing | Saving Earth
https://www.britannica.com/explore/savingearth/scientific-alternatives-to-animal-testing-a-progress-report
The European Union recently approved a replacement for the Draize test called the EpiSkin® test, which is an in vitro method that uses test-tube-sized models of ...
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28 Can we do science without animal testing? - YouTube
https://www.youtube.com/watch?v=2hxUMpYFo_Y
Jul 10, 2017
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29 Alternatives to Animal Testing
https://www.edqm.eu/alternatives-to-animal-testing
... for such purposes and it encourages not to experiment on animals except where there is no alternative and it promotes research into alternative methods.
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30 Alternatives to Animal Testing and Research
https://fbresearch.org/biomedical-research/alternatives-to-animal-testing/
Cell cultures and computers are limited in what they can model. A cell culture is not a full living system, like an animal or person, so it doesn't show how a ...
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31 Animal Testing: Why the FDA Is Exploring More Alternatives
https://www.healthline.com/health-news/animal-testing-why-the-fda-is-exploring-more-alternatives
The FDA is moving away from animal testing and considering a number of alternatives · Alternatives include organ-on-a-chip technology, cell ...
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32 Three researchers seeking alternatives | Karolinska Institutet
https://ki.se/en/research/three-researchers-seeking-alternatives
Animal testing is a part of medical research. However, work is continuously ongoing to reduce the number of animals, improve technology and replace animal ...
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33 Tiny organs as an alternative to animal testing
https://www.mdc-berlin.de/news/news/tiny-organs-alternative-animal-testing
Hopes are high that these mini-organs will revolutionize medical research and gradually obviate the need for animal experiments. The motives for ...
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34 Animal Research in the Federal Government: A Search for ...
https://www.gao.gov/blog/animal-research-federal-government-search-alternatives
Developing alternatives to animal use in testing ... However, we found that the agencies have not routinely measured the effect of their ...
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35 An alternative to animal experiments - ScienceDaily
https://www.sciencedaily.com/releases/2020/10/201014140956.htm
An alternative to animal experiments. New applications for organoids from human intestinal tissue. Date: October 14, 2020; Source: Technical University of ...
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36 Animal Use Alternatives (3Rs) | National Agricultural Library
https://www.nal.usda.gov/animal-health-and-welfare/animal-use-alternatives
The “3Rs alternatives” refers to the replacement, reduction, and refinement of animals used in research, teaching, testing, and exhibition.
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37 NIST Study Gives Animal Testing Alternatives a Confidence ...
https://www.nist.gov/news-events/news/2022/05/nist-study-gives-animal-testing-alternatives-confidence-boost
The researchers built upon on an existing method, improving its efficiency, accessibility and quality controls. Using the new animal-free ...
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38 The Many Benefits of Using Alternatives to Animal Testing
https://www.invitrointl.com/blog/the-many-benefits-of-using-alternatives-to-animal-testing/
Animal testing was the mainstay when it came to creating products that were safe for humans, primarily because there simply were no ...
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39 Scholarly Articles on Animal Experimentation - Gale
https://www.gale.com/open-access/animal-experimentation
In the following viewpoint, the American Anti-Vivisection Society (AAVS) declares that experimentation on animals is not a valid means of testing treatments for ...
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40 Medical development without animal testing is the goal, but ...
https://www.washingtonpost.com/opinions/2021/11/02/medical-development-without-animal-testing-is-goal-were-not-there-yet/
Physicians, researchers and regulators, however, understand that her proposal to use new technologies as alternatives to animal research is not ...
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41 Recycling human skin: An alternative to animal testing?
https://www.france24.com/en/tv-shows/down-to-earth/20201106-recycling-human-skin-an-alternative-to-animal-testing
For more than half a century, humans have required all new drugs to be tested on animals. Today, ethical alternatives are emerging.
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42 Let's be open and honest, animal testing remains necessary
https://www.maastrichtuniversity.nl/news/let%E2%80%99s-be-open-and-honest-animal-testing-remains-necessary
Without laboratory animal research, our doctors and researchers can no longer develop new or improved treatments including drugs or vaccines.
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43 Welcome Alternatives to Animal Testing
https://www.genengnews.com/commentary/point-of-view/welcome-alternatives-to-animal-testing/
Time and again, drugs and vaccines that proved promising in animal tests failed when tried in humans. At least 172 drugs that showed promise in ...
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44 Why Do Scientists Use Animals in Research
https://www.physiology.org/career/policy-advocacy/animal-research/Why-do-scientists-use-animals-in-research
Scientists study animals when there is no alternative and it is ... If the new therapy seems promising, it is then tested in animals to see whether it seems ...
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45 Alternatives to Animal Experimentation:
https://web.wpi.edu/Pubs/E-project/Available/E-project-101118-070008/unrestricted/Animal_Alternatives_Final_Report_PDFA.pdf
However, recent studies comparing results of animal testing to use of alternatives have shown that genetically different animals do not always ...
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46 Animal Testing | Pros & Cons | ProCon.org
https://animal-testing.procon.org/
Proponents of animal testing say that it has enabled the development of many life-saving treatments for both humans and animals, that there is no alternative ...
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47 Replacement of Animal Procedures: Alternatives in Testing ...
https://thedermreview.com/replacement-of-animal-procedures-alternatives-in-testing-research-and-education/
Evidence of animals being used in experiments goes back to the 1500s. However, it was not until 1959 that thoughts about the ethics of using ...
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48 Innovative Human Three-Dimensional Tissue-Engineered ...
https://www.mdpi.com/2306-5354/7/3/115
The replacement of animal testing in research can be achieved through ... up as an alternative to in vivo Draize rabbit eye and skin irritation tests [35].
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49 Alternatives to animal testing: current status and future ...
https://link.springer.com/article/10.1007/s00204-011-0718-x
2004). These numbers are an economic as well as an ethical call for alternative methods replacing animal testing. ZEBET has been already ...
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50 Replacement of animal procedures: alternatives in research ...
https://journals.sagepub.com/doi/pdf/10.1258/002367794780681714
the actual experiment} and absolute replacement} in which animals would not be required at any stage at all. Laboratory Animals (1994) 28, 193-211 ...
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51 Uncovering alternatives to animal testing | Alumni & Friends
https://alumni-friends.brown.edu/news/2021-06-16/animal-testing-alternatives
Uncovering alternatives to animal testing ... Brown researchers are pursuing a promising new method that could transform toxicology testing, ...
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52 Alternatives to Experimenting on Animals - PETA India
https://www.petaindia.com/issues/animals-experimentation/alternatives-to-experimenting-on-animals/
In Vitro Testing In vitro tests allow researchers to predict more accurately how drugs, chemicals, cosmetics, and other consumer products will affect humans.
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53 Animal Testing Alternatives: Online Resources
http://www.istl.org/00-summer/internet.html
Research scientists who are using animals as test subjects are required by the Animal Welfare Act (7 USC 2131-2156) to consider alternatives to animal testing ...
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54 Animal Testing? - PETA Science Consortium International e.V.
https://www.thepsci.eu/wp-content/uploads/2018/05/BBC-Focus_animal-testing.pdf
studies, animal experiments are no longer the best way forward. ... cologist and the director of the Center for Alternatives to Animal Testing at Johns ...
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55 Alternatives to Animals
http://animalresearch.thehastingscenter.org/facts-sheets/alternatives-to-animals/
In vitro testing, Cells or tissue samples taken from animals or humans and prepared for laboratory study, Drug research, testing new chemicals and products on ...
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56 Replacing animal testing: the why and the how – PrecisionTox
https://precisiontox.org/replacing-animal-testing-the-why-and-the-how/
Another solution to replace animals testing relies on alternative organism species. The replacement of animal models with other animal models ...
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57 FRAME: Researching Alternatives to Animal Testing
https://frame.org.uk/
FRAME believes in and champions the development of better scientific methods for the benefit of humans and animals.
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58 Alternatives to Animal Research - Pro-Test Germany
https://www.pro-test-deutschland.de/en/themen/alternativen-zu-tierversuchen/
Dr. Stephens says that in vitro tests do not replace animal testing altogether. The reason for this is clear. A new drug may work in a cell culture or ...
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59 Replacing animal testing with cultured human cells - Euronews
https://www.euronews.com/next/2016/10/10/replacing-animal-testing-with-cultured-human-cells
These new technologies are not simply a replacement of an animal test. They are a new toolbox for being able to tackle research questions in ...
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60 Should animals be used in research? - YourGenome
https://www.yourgenome.org/debates/should-animals-be-used-in-research/
No · Eventually, it should be optional to use animals in drug testing. · More funding should be put into developing alternatives to experiments ...
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61 Why don't researchers use alternative methods more frequently?
https://naturalsciences.ch/animal-experimentation-explained/alternative_methods/use
When researchers apply for approval for an animal experiment, they must justify why they do not use non-animal methods. Such alternative methods are used ...
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62 Can Organs-on-a-chip Replace Animal Testing? - Cellix Ltd
https://www.wearecellix.com/post/can-organs-on-a-chip-replace-animal-testing
Relative replacement still uses animals that are not submitted to any kind of distress during the experiment, while absolute replacement ...
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63 An Alternative to Animal Testing in Pharmaceuticals?
https://www.iflscience.com/alternative-animal-testing-pharmaceuticals-24045
Currently, before a new compound or drug can even enter clinical trials on humans, it has to be tested on non-human animals. Pharmaceutical ...
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64 Can we end animal testing? | BBC Science Focus Magazine
https://www.sciencefocus.com/nature/can-we-end-animal-testing/
Animal welfare activists have long insisted that researchers jettison research on animals for alternative methods, such as human stem cells grown in a dish, ...
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65 Biomedical innovation and ethics: alternatives to animal testing
https://www.scielo.br/j/bioet/a/v7DM3HrLjjKYYPrZy8nz3Cs/?format=pdf&lang=en
The use of non-human animals has been incorporated into scientific practices as an essential biomedical research tool and in industry tests for human ...
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66 Let them go, let them go ! - Omniscience - MyScienceWork
https://www.mysciencework.com/omniscience/let-go-let-go
A study published by Marcel Leist and his colleagues in Alternatives to Animal Experimentation: ALTEX reminds us that 9 out of 10 drugs fail ...
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67 Alternatives to the Use of Animals in Research - MSPCA-Angell
https://www.mspca.org/animal_protection/lab-animal-alternatives-the-three-rs/
An increasing number of alternatives now offers new hope for the welfare of millions of animals used in biomedical research, product safety testing, ...
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68 What Is Animal Testing? Is It Cruel and What ... - Sentient Media
https://sentientmedia.org/animal-testing/
Alternatives to Animal Testing · In Vitro Testing · Computer Modeling · Research Using Human Volunteers · Human Tissues.
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69 Using Computer Models To Replace Animal Tests For Heart ...
https://faunalytics.org/using-computer-models-as-animal-replacements-for-heart-disease/
One alternative to animal testing is the use of human-based computer models. If such models are proven to be effective, they can replace ...
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70 Alternatives to Animal Testing - PETA Asia
https://www.petaasia.com/issues/experimentation/alternatives/
Non-animal methods are not hindered by species differences that make applying animal test results to humans difficult or impossible, and they usually take ...
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71 Is it time to replace one of the cornerstones of animal research?
https://www.science.org/content/article/it-time-replace-one-cornerstones-animal-research
An IACUC [Institutional Animal Care and Use Committee], for example, might ask an investigator to detail the science showing that animal alternatives like organ ...
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72 Alternative Test Methods and Strategies to Reduce Vertebrate ...
https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce
promote the development and timely incorporation of alternative test methods or strategies that do not require new vertebrate animal testing.
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73 Reducing Animal Testing Using Stem Cells - C&EN
https://cen.acs.org/articles/85/i3/Reducing-Animal-Testing-Using-Stem.html
Whether they are being used as an alternative to animals in toxicology testing or disease modeling, embryonic stem cells will, many researchers hope, offer an ...
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74 CCAC training module: Three Rs of humane animal ...
https://www.ccac.ca/Documents/Education/Modules/Core_Stream/CCAC_training_module_on_Three_Rs_of_humane_animal_experimentation.pdf
were searched to confirm that there are no alternatives to animals. ... General Principles Concerning Replacement in Research, Testing, and Teaching.
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75 Citizens for Alternatives to Animal Research
https://www.caareusa.org/
It is now possible to conduct a vast array of experiments without using animals and derive results that are faster, cheaper and more relevant to human medicine.
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76 Zebra Fish Model as an Alternative to Animal Testing: A Review
https://www.tridhascholars.org/pdfs/zebra-fish-model-as-an-alternative-to-animal-testing-a-review-PCI-04-1037.pdf
Alternatives to animal testing were planned to overcome some of the drawbacks related with animal experiments and evade the unethical procedures ...
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77 University spinout provides compelling alternative to animal ...
https://www.dundee.ac.uk/stories/university-spinout-provides-compelling-alternative-animal-testing
... and cosmetics testing with their spinout venture that offers an alternative for many experiments currently only performed in animals.
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78 Reducing and replacing animal tests — Ghent University
https://www.ugent.be/en/research/science-society/labanimals/alternatives.htm
Alternative techniques are, simply put, techniques that do not involve the use of animal research or testing. Not every alternative method that is 'free of ...
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79 Searching for Alternatives and the 3Rs - FSU Office of Research
https://www.research.fsu.edu/research-offices/acuc/alternatives_3rs/
What are Alternatives? The use of animals remains necessary except where valid scientific alternative methods are available. The concept of alternatives was ...
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80 Alternatives to animal testing - WUR
https://www.wur.nl/en/article/alternatives-to-animal-testing.htm
Through these innovations Wageningen University & Research has been able to replace 80 per cent of standard animal tests with an animal cruelty-free ...
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81 Frequently Asked Questions | Animal Research
https://www.animalresearch.pitt.edu/frequently-asked-questions
Animal testing is not an alternative to testing in humans. Rather, it is an important complementary part of the effort to find new therapies.
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82 Animals in Research | General Considerations - ASPCA
https://www.aspca.org/about-us/aspca-policy-and-position-statements/animals-research-general-considerations
The ASPCA strongly supports the development and validation of alternative methods to the use of animals in biomedical research and testing.
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83 Non-Animal Research Methods and Tests - PETA UK
https://www.peta.org.uk/issues/animals-not-experiment-on/non-animal-research-methods/
These modern methods include sophisticated tests using human cells and tissues (also known as in vitro methods), advanced computer-modelling techniques (often ...
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84 Alternatives to Animal Testing in Food Safety, Nutrition and ...
https://ilsi.eu/scientific-activities/food-safety/alternatives-to-animal-testing-in-food-safety-nutrition-and-efficacy-studies/
What are the challenges to use vital human material as an innovative approach to move towards human-based science and avoid animal research & testing? - Ongoing ...
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85 Is It Time to End Animal Testing?: How Technology Can ...
https://interestingengineering.com/science/is-it-time-to-end-animal-testing-how-technology-can-replace-animals
Animals have been the go-to test subjects for experiments for decades, but we don't need to continue this controversial practice any longer.
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86 Animals Used in Research - Animal Legal Defense Fund
https://aldf.org/focus_area/animals-used-in-research/
On top of that, animal testing does not achieve its intended results. According to the U.S. Food and Drug Administration (FDA), just 8% of drugs tested on ...
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87 Why Animal Research? - Stanford Medicine
https://med.stanford.edu/animalresearch/why-animal-research.html
There are several reasons why the use of animals is critical for biomedical research: ... Animals are biologically very similar to humans. In fact, mice share ...
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88 Genoskin reduces animal testing by using donated human skin
https://genoskin.com/en/animal-testing/
Reducing animal testing with human skin tissue. Ex vivi human skin models as an alternative to animal testing: picto rabbit ...
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89 What's more effective: human or animal studies?
https://www.jax.org/why-the-mouse/effective
The answer is both: Better together! Animal testing is not an alternative to human trials, it complements it. Medieval castles had high walls and soldiers in ...
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90 Working Toward an Alternative to Animal Testing
https://www.communitycatspodcast.com/center-for-contemporary-sciences-working-toward-an-alternative-to-animal-testing/
It's hard to avoid using products that are tested on animals, and at the moment, drugs and vaccines we need don't have an alternative method of ...
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91 Better Science - Alternatives - Project R&R
https://www.releasechimps.org/better-science/alternatives
Animal experiments actually can be of no use and even harmful to human health. They have produced misleading information that has resulted in dangerous ...
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92 How science is getting closer to a world without animal testing
https://www.ft.com/content/7c35e08a-4931-4401-b27e-acabf974bff8
Then the cell therapy hit a snag: it did not work when tested on mice. ... head of the Center for Alternatives to Animal Testing at Johns ...
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93 Ethical medical research/Alternatives to animal testing
https://en.wikiversity.org/wiki/Ethical_medical_research/Alternatives_to_animal_testing
Alternatives to animal testing make use of medical imaging, microdosing, metabolism simulation, biochips, mathematics, visualizations and other methods. These ...
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94 About Animal Research in Medicine
https://tnprc.tulane.edu/about-animal-research-medicine
Development of any new medicine requires testing in animals to determine if ... The Committee scrutinizes research proposals to ensure that alternatives to ...
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95 How animal testing is minimised - The Guardian
https://www.theguardian.com/science/2010/dec/31/animal-research-alternatives
The approach to finding alternatives to animals in scientific procedures is widely ... and one day potentially no, animals" in experiments.
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96 Animals Used in Research - Pfizer
https://www.pfizer.com/science/clinical-trials/integrity-and-transparency/animals-used-in-research
The use of animals in research is currently an essential component of the drug ... Pfizer is also committed to the use of alternative testing methods ...
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